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BNCT is biochemically targeted radiation therapy. Boron-10 (10B) atoms are selectively delivered to the tumor, followed by irradiation with epithermal neutrons (nth). A nuclear reaction occurs, when a 10B atom captures a neutron. The short range of the reaction products restricts most of the radiation dose to the boron-loaded cells.[/vc_column_text][vc_empty_space height=”20″][vc_column_text]
The stable boron isotope 10B has a large neutron capture radius. Thus 10B is more likely to capture neutrons than many other elements that are present in biological environments (e.g. nitrogen and hydrogen). A fission reaction occurs upon neutron capture, and a lithium ion and an alpha particle are produced. These particles have high kinetic energies, but their range is only about 10 microns. This leads to very efficient cancer cell killing precisely at the site of boron accumulation.[/vc_column_text][vc_empty_space height=”20″][/vc_column][vc_column width=”1/2″][vc_single_image image=”14″ img_size=”557×422″ alignment=”center” onclick=”link_image” qode_css_animation=”element_from_right” qode_hover_animation=”zoom_in”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”grid” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern” background_color=”#ffffff” padding_top=”25″][vc_column width=”1/2″][vc_column_text]
Potential
Has been in previous studies curative for 15-20% of terminal phase patients, despite using sub-optimal boron carrier
Can be used to treat many kinds of solid tumors that can be boron loaded
Affects healthy tissues less than conventional radiation therapy
Can be used in combination with other treatments
Cost-effective
Low number of treatment sessions
Short hospital period – outpatient in many cases
Can be repeated
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Boron Neutron Capture reaction leads to intense local irradiation precisely at the site of boron accumulation, which leads to tumor necrosis[/vc_column_text][vc_empty_space height=”20″][vc_column_text]
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