Improving the boron carrier is one of the biggest challenges in BNCT:
between tumor and surrounding healthy tissue should be significantly increased.
cells should be significantly increased.
of the boron carrier to the tumor cells (carrier cell surface affinity and/or cell internalisation) should be significantly improved.
of the boron carrier should allow for a long retention in the tumor cells.
In addition to the lead molecule, Tenboron has two other carrier development programs.